OR5P3

Across TCGA cell cohorts, OR5P3 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5P3-associated genes across cancer lineages are NLRP2B, MSGN1, and SPRR2F. Each is linked with OR5P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5P3-to-partner and partner-to-OR5P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NLRP2B grouped by OR5P3-low versus OR5P3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5P3→partner) and Y-score (partner→OR5P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	NLRP2B →	+0.012	+3.882	<.001	.001	3	2
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	SPRR2F →	+0.521	+4.029	.001	.002	3	1
LARGE_INTESTINE	PIK3R6 →	+0.045	+3.409	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

NLRP2B by OR5P3 expression — SKIN

Explore this box plot interactively →