OR5M9

Across TCGA patient cohorts, OR5M9 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5M9-associated genes across cancer lineages are PRDX1, beta-Catenin, and FOXO3a_pS318_S321. Each is linked with OR5M9 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M9-to-partner and partner-to-OR5M9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRDX1 grouped by OR5M9-low versus OR5M9-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M9→partner) and Y-score (partner→OR5M9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PRDX1 →	-0.343	-2.990	.017	.036	3	1
SKCM	beta-Catenin →	-0.545	-3.321	.043	.010	3	1
UCEC	FOXO3a_pS318_S321 →	-0.147	-2.321	.019	.035	3	1
UCEC	mTOR_pS2448 →	-0.149	-2.321	.046	.035	3	1
UCEC	Rictor_pT1135 →	-0.129	-3.169	.012	.019	3	1
UCEC	Tuberin →	+0.373	+3.009	.005	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

PRDX1 by OR5M9 expression — LUSC

Explore this box plot interactively →