OR5M9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR5M9 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5M9-associated genes across cancer lineages are CRYBB1, IFNA6, and CAPN11. Each is linked with OR5M9 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M9-to-partner and partner-to-OR5M9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB1 grouped by OR5M9-low versus OR5M9-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M9→partner) and Y-score (partner→OR5M9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADCRYBB1 →+0.040+2.536<.001.00731
LUNG_NSCLC_LUADIFNA6 →+0.008+2.887.001.00931
LUNG_NSCLC_LUADCAPN11 →+0.050+2.752.007.00631
LUNG_NSCLC_LUADOR2T33 →+0.424+2.803.002.00331
LUNG_NSCLC_LUADOR6T1 →+0.016+2.887.001.00931
LUNG_NSCLC_LUADIFNA14 →+0.012+3.662<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

CRYBB1 by OR5M9 expression — LUNG_NSCLC_LUAD

Box plot of CRYBB1 in OR5M9-low vs OR5M9-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration