OR5M8

Across TCGA cell cohorts, OR5M8 mutation is significantly associated with the drug of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5M8-associated genes across cancer lineages are BMS-536924, NPK76-II-72-1, and THZ-2-49. Each is linked with OR5M8 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M8-to-partner and partner-to-OR5M8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMS-536924 grouped by OR5M8-low versus OR5M8-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M8→partner) and Y-score (partner→OR5M8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BMS-536924 →	-0.607	-2.743	.024	.046	3	1
LARGE_INTESTINE	NPK76-II-72-1 →	-0.507	-2.740	.047	.045	3	1
LARGE_INTESTINE	THZ-2-49 →	-0.900	-2.736	.014	.044	2	1
LARGE_INTESTINE	Bromosporine →	-0.323	-2.743	.048	.046	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

BMS-536924 by OR5M8 expression — LARGE_INTESTINE

Explore this box plot interactively →