Across TCGA pan-cancer cohorts, OR5M5P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR5M5P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR5M5P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR5M5P is over-expressed in tumor.
LUSC and COAD are the cancer types where OR5M5P tumor–normal differential expression is most reproducible.