OR5M3

Across TCGA patient cohorts, OR5M3 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5M3-associated genes across cancer lineages are FASN, p62 Lck ligand, and PDCD4. Each is linked with OR5M3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5M3-to-partner and partner-to-OR5M3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by OR5M3-low versus OR5M3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M3→partner) and Y-score (partner→OR5M3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.372	+2.321	.022	.006	3	2
UCEC	p62 Lck ligand →	+0.323	+1.807	.016	.027	3	2
UCEC	PDCD4 →	-0.513	-2.449	.008	.019	3	2
UCEC	Src_pY527 →	-0.491	-2.311	.005	.034	3	2
UCEC	ASNS →	+0.392	+2.999	.008	.035	3	2
UCEC	Caspase-7-cleavedD198 →	+0.788	+2.479	.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

FASN by OR5M3 expression — UCEC

Explore this box plot interactively →