OR5M3

Across TCGA cell cohorts, OR5M3 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5M3-associated genes across cancer lineages are OR52A5, NPAP1, and LCE4A. Each is linked with OR5M3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M3-to-partner and partner-to-OR5M3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52A5 grouped by OR5M3-low versus OR5M3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M3→partner) and Y-score (partner→OR5M3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR52A5 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	NPAP1 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	LCE4A →	+0.040	+3.700	<.001	.009	3	1
LARGE_INTESTINE	KRTAP5-3 →	+0.030	+3.217	<.001	.006	3	1
LARGE_INTESTINE	PRAMEF9 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	IFNA14 →	+0.020	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

OR52A5 by OR5M3 expression — LARGE_INTESTINE

Explore this box plot interactively →