Across TCGA pan-cancer cohorts, OR5M2P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of OR5M2P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR5M2P RNA is repressed in tumor relative to normal tissue. In most cancer types OR5M2P is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
KIRC are the cancer types where OR5M2P tumor–normal differential expression is most reproducible.