OR5M11

Across TCGA patient cohorts, OR5M11 mutation is significantly associated with the RNA expression of many other genes, with 1,425 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5M11-associated genes across cancer lineages are MTA2, PDXDC1, and ZNF501. Each is linked with OR5M11 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5M11-to-partner and partner-to-OR5M11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTA2 grouped by OR5M11-low versus OR5M11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M11→partner) and Y-score (partner→OR5M11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTA2 →	+0.389	+1.829	.002	.008	3	3
UCEC	PDXDC1 →	+0.461	+2.947	.003	<.001	3	2
UCEC	ZNF501 →	+0.560	+2.230	.001	.006	3	2
UCEC	USP7 →	+0.365	+2.815	.004	.001	3	2
UCEC	HYKK →	+0.374	+1.776	<.001	.008	3	2
UCEC	DCLRE1A →	+0.455	+2.639	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,425 associations by consensus.

MTA2 by OR5M11 expression — UCEC

Explore this box plot interactively →