OR5M11

Across TCGA patient cohorts, OR5M11 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5M11-associated genes across cancer lineages are Caveolin-1, p90 RSK_pT359_S363, and eIF4G. Each is linked with OR5M11 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M11-to-partner and partner-to-OR5M11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveolin-1 grouped by OR5M11-low versus OR5M11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M11→partner) and Y-score (partner→OR5M11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caveolin-1 →	-0.627	-1.906	.031	.016	3	2
LUSC	p90 RSK_pT359_S363 →	-0.147	-2.990	.038	.036	3	1
UCEC	eIF4G →	+0.295	+2.000	.018	.030	3	1
UCEC	MEK1 →	+0.368	+3.459	.012	.005	3	1
UCEC	Akt_pS473 →	+0.591	+2.459	.040	.019	3	1
UCEC	p27_pT198 →	+0.088	+1.906	.041	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Caveolin-1 by OR5M11 expression — UCEC

Explore this box plot interactively →