OR5M11

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR5M11 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OR5M11-associated genes across cancer lineages are DAZ1, USP17L7, and ATP1B4. Each is linked with OR5M11 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M11-to-partner and partner-to-OR5M11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAZ1 grouped by OR5M11-low versus OR5M11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M11→partner) and Y-score (partner→OR5M11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEDAZ1 →+0.706+3.758<.001.00731
LARGE_INTESTINEUSP17L7 →+0.085+4.013<.001.00131
STOMACHATP1B4 →+0.012+4.285<.001.00731
STOMACHTOPAZ1 →+0.022+4.285<.001.00731
STOMACHOR52N4 →+0.086+4.129<.001.00731
STOMACHOR2T4 →+0.082+4.285<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

DAZ1 by OR5M11 expression — LARGE_INTESTINE

Box plot of DAZ1 in OR5M11-low vs OR5M11-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration