OR5M10

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR5M10 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR5M10 data layer compared with 7 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OR5M10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR5M10 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, UCEC, and LIHC are the cancer types where OR5M10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianAll0.4360.844<.00125view →
UCECDFSMedianAll1.0000.625.02912view →
LIHCOSMedianII,III,IV0.1180.716.00312view →
COADOSMedianAll0.1600.613.0306view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OR5M10–LUAD (OS)

Kaplan–Meier survival curve for OR5M10 mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration