OR5M10

Across TCGA patient cohorts, OR5M10 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5M10-associated genes across cancer lineages are Rab25, EGFR_pY1068, and mTOR_pS2448. Each is linked with OR5M10 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M10-to-partner and partner-to-OR5M10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rab25 grouped by OR5M10-low versus OR5M10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M10→partner) and Y-score (partner→OR5M10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.395	-3.584	.004	.002	3	2
UCEC	EGFR_pY1068 →	-0.308	-2.584	.003	.010	3	2
UCEC	mTOR_pS2448 →	-0.159	-2.222	.012	.011	3	2
UCEC	PKC-delta_pS664 →	-0.207	-4.000	<.001	<.001	3	2
UCEC	Shc_pY317 →	-0.240	-2.906	<.001	.001	3	2
UCEC	STAT3_pY705 →	-0.463	-2.459	<.001	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Rab25 by OR5M10 expression — UCEC

Explore this box plot interactively →