OR5M1

Across TCGA cell cohorts, OR5M1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5M1-associated genes across cancer lineages are OR6N1, TXNDC8, and OR9G4. Each is linked with OR5M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M1-to-partner and partner-to-OR5M1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6N1 grouped by OR5M1-low versus OR5M1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M1→partner) and Y-score (partner→OR5M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR6N1 →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	TXNDC8 →	+0.013	+5.087	<.001	.004	3	1
LUNG_SCLC	OR9G4 →	+0.119	+5.029	<.001	.006	3	1
LUNG_SCLC	FTMT →	+0.177	+5.029	<.001	.006	3	1
LARGE_INTESTINE	SYT10 →	+0.348	+4.196	<.001	.002	3	1
LARGE_INTESTINE	KRT85 →	+0.639	+3.823	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR6N1 by OR5M1 expression — URINARY_TRACT

Explore this box plot interactively →