OR5L2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5L2 mutation is significantly associated with the RNA expression of many other genes, with 2,005 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OR5L2-associated genes across cancer lineages are ADNP2, RNASEH2A, and WRAP53. Each is linked with OR5L2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR5L2-to-partner and partner-to-OR5L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5L2→partner) and Y-score (partner→OR5L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECADNP2 →+0.669+2.625.001.00534
LUSCRNASEH2A →+0.452+2.333.002.00334
LUADWRAP53 →+0.359+3.193.008.00934
SKCMSAAL1 →+0.385+2.331.006.00333
LUSCMORN4 →+0.451+2.035.002.00533
UCECACD →+0.607+3.606<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,005 associations by consensus.

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