Across TCGA patient cohorts, OR5L2 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR5L2-associated genes across cancer lineages are FoxM1, p27, and Src. Each is linked with OR5L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5L2-to-partner and partner-to-OR5L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5L2→partner) and Y-score (partner→OR5L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FoxM1 →	+0.266	+3.012	.048	.018	2	2
LUAD	p27 →	-0.179	-3.169	.019	.019	3	1
LUAD	Src →	+0.274	+3.012	.007	.018	3	1
LUSC	JNK_pT183_Y185 →	-0.099	-2.284	.026	.031	3	1
LUSC	p27_pT198 →	+0.145	+1.709	.010	.026	3	1
LUSC	PDK1 →	-0.110	-3.000	.021	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

OR5L2 survival (RNA) · tumor vs normal (RNA) · all OR5L2 data types