Across TCGA cell cohorts, OR5L2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR5L2-associated genes across cancer lineages are TEX13D, MARCO, and CGB8. Each is linked with OR5L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5L2-to-partner and partner-to-OR5L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5L2→partner) and Y-score (partner→OR5L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TEX13D →	+0.049	+3.514	.007	.008	3	1
LUNG_SCLC	MARCO →	+0.396	+3.762	.006	.003	3	1
LUNG_SCLC	CGB8 →	+1.338	+3.256	<.001	.005	3	1
LUNG_SCLC	SPANXB1 →	+2.146	+3.621	<.001	.005	3	1
LUNG_SCLC	SLFN14 →	+0.024	+3.830	<.001	.005	3	1
LUNG_SCLC	LBHD2 →	+0.502	+3.070	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

OR5L2 survival (RNA) · tumor vs normal (RNA) · all OR5L2 data types