OR5L1

Across TCGA cell cohorts, OR5L1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR5L1-associated genes across cancer lineages are CEACAM4, CLDN14, and GKN1. Each is linked with OR5L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5L1-to-partner and partner-to-OR5L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEACAM4 grouped by OR5L1-low versus OR5L1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5L1→partner) and Y-score (partner→OR5L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CEACAM4 →	+0.013	+4.906	<.001	.006	3	1
LUNG_SCLC	CLDN14 →	+0.348	+3.928	<.001	.001	3	1
LUNG_SCLC	GKN1 →	+0.157	+3.196	<.001	.001	3	1
LUNG_SCLC	OR10A4 →	+0.035	+2.993	<.001	.002	3	1
LUNG_SCLC	PSG6 →	+0.041	+2.938	.001	.003	3	1
LUNG_SCLC	NKX2-6 →	+0.025	+2.847	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

CEACAM4 by OR5L1 expression — OESOPHAGUS

Explore this box plot interactively →