OR5K3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5K3 mutation is significantly associated with the RNA expression of many other genes, with 2,141 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5K3-associated genes across cancer lineages are RNA5SP499, RPS29P32, and CCL5. Each is linked with OR5K3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5K3-to-partner and partner-to-OR5K3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5K3→partner) and Y-score (partner→OR5K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP499 →+0.097+3.890<.001.00733
COADRPS29P32 →+0.623+4.666<.001.00532
UCECCCL5 →+1.488+3.823<.001<.00132
UCECMIR7702 →+0.181+3.890<.001.00732
LUADTNFSF8 →+0.774+3.217.003.00932
LUADLSP1P3 →+0.223+2.896<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,141 associations by consensus.

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