Across TCGA cell cohorts, OR5K3 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR5K3-associated genes across cancer lineages are OR8B12, RD3L, and IQCJ. Each is linked with OR5K3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5K3-to-partner and partner-to-OR5K3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5K3→partner) and Y-score (partner→OR5K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR8B12 →	+0.036	+5.029	<.001	.006	3	1
LUNG_SCLC	RD3L →	+0.018	+5.029	.004	.006	3	1
BLOOD_Leukemia	IQCJ →	+0.662	+4.276	<.001	.007	3	1
SKIN	APOBEC3A →	+0.316	+3.660	.005	.005	3	1
SKIN	C8orf74 →	+0.070	+3.345	<.001	.007	3	1
SKIN	HES5 →	+0.057	+4.155	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

OR5K3 survival (RNA) · tumor vs normal (RNA) · all OR5K3 data types