Across TCGA cell cohorts, OR5K3 mutation is significantly associated with the mutation status of many other genes, with 2,609 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5K3-associated genes across cancer lineages are KATNIP, TOP1MT, and PCDHA11. Each is linked with OR5K3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR5K3-to-partner and partner-to-OR5K3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5K3→partner) and Y-score (partner→OR5K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KATNIP →	+3.145	+3.932	.004	.004	1	4
CNS	TOP1MT →	+5.044	+5.614	.003	.003	1	3
SKIN	PCDHA11 →	+2.313	+3.282	.007	.007	1	3
BLOOD_Leukemia	PTCHD4 →	+4.238	+5.662	<.001	<.001	1	3
BLOOD_Leukemia	GLYATL1 →	+4.560	+4.870	<.001	<.001	1	3
BLOOD_Lymphoma	ADGRE1 →	+5.014	+5.584	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,609 associations by consensus.

Exploration

OR5K3 survival (RNA) · tumor vs normal (RNA) · all OR5K3 data types