OR5J2

Across TCGA patient cohorts, OR5J2 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5J2-associated genes across cancer lineages are Cyclin-E2, ASNS, and c-Kit. Each is linked with OR5J2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR5J2-to-partner and partner-to-OR5J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-E2 grouped by OR5J2-low versus OR5J2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5J2→partner) and Y-score (partner→OR5J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-E2 →	+0.153	+1.700	.032	.044	3	4
LUSC	ASNS →	+0.502	+2.179	.017	.035	3	2
SKCM	c-Kit →	-0.614	-2.321	.026	.033	3	2
UCEC	MEK1 →	+0.491	+4.000	.001	<.001	3	2
UCEC	STAT3_pY705 →	-0.509	-2.700	<.001	.005	3	2
LUAD	Bap1-c-4 →	+0.206	+2.186	.029	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Cyclin-E2 by OR5J2 expression — UCEC

Explore this box plot interactively →