OR5J2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR5J2 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5J2-associated genes across cancer lineages are COX6A2, RNASE9, and OR6N1. Each is linked with OR5J2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5J2-to-partner and partner-to-OR5J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX6A2 grouped by OR5J2-low versus OR5J2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5J2→partner) and Y-score (partner→OR5J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTCOX6A2 →+0.123+5.087<.001.00431
URINARY_TRACTRNASE9 →+0.016+5.087<.001.00431
URINARY_TRACTOR6N1 →+0.013+5.087<.001.00431
URINARY_TRACTIFNA14 →+0.026+5.087<.001.00431
LARGE_INTESTINEOR4D1 →+0.006+3.217<.001.00631
LARGE_INTESTINEDMP1 →+0.055+3.137<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

COX6A2 by OR5J2 expression — URINARY_TRACT

Box plot of COX6A2 in OR5J2-low vs OR5J2-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration