OR5H2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5H2 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5H2-associated genes across cancer lineages are AMPK_alpha, Notch1, and PDCD4. Each is linked with OR5H2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5H2-to-partner and partner-to-OR5H2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H2→partner) and Y-score (partner→OR5H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMAMPK_alpha →+0.140+1.874.014.04932
UCECNotch1 →+0.180+3.009.010.01931
UCECPDCD4 →-0.725-2.321.002.03522
UCECASNS →+0.617+2.321<.001.03522
UCECATM →-0.527-2.321.020.03531
UCEC4E-BP1 →+0.342+3.459.011.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration