OR5H15

Across TCGA patient cohorts, OR5H15 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5H15-associated genes across cancer lineages are PCNA, ASNS, and EGFR_pY1068. Each is linked with OR5H15 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5H15-to-partner and partner-to-OR5H15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by OR5H15-low versus OR5H15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H15→partner) and Y-score (partner→OR5H15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.260	+2.584	.009	.011	3	2
UCEC	ASNS →	+0.429	+3.169	.010	.019	3	2
UCEC	EGFR_pY1068 →	-0.266	-3.321	.023	.010	3	1
UCEC	FOXO3a_pS318_S321 →	-0.116	-2.312	.046	.034	3	1
UCEC	mTOR_pS2448 →	-0.203	-3.302	.003	.010	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.462	-2.571	.027	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

PCNA by OR5H15 expression — UCEC

Explore this box plot interactively →