OR5H14

Across TCGA patient cohorts, OR5H14 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5H14-associated genes across cancer lineages are Rictor_pT1135, Cyclin-B1, and JNK2. Each is linked with OR5H14 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5H14-to-partner and partner-to-OR5H14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rictor_pT1135 grouped by OR5H14-low versus OR5H14-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H14→partner) and Y-score (partner→OR5H14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Rictor_pT1135 →	-0.153	-3.000	.022	.034	3	2
UCEC	Cyclin-B1 →	+0.779	+2.222	.001	.011	3	2
UCEC	JNK2 →	+0.307	+2.906	<.001	.001	3	2
UCEC	TFRC →	+0.459	+3.000	.041	.036	3	2
UCEC	Tuberin →	+0.421	+3.321	<.001	.009	3	2
SKCM	Tuberin_pT1462 →	-0.325	-2.115	.007	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Rictor_pT1135 by OR5H14 expression — SKCM

Explore this box plot interactively →