OR5H14

Across TCGA cell cohorts, OR5H14 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5H14-associated genes across cancer lineages are OR2M5, TMEM95, and NPY2R. Each is linked with OR5H14 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5H14-to-partner and partner-to-OR5H14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2M5 grouped by OR5H14-low versus OR5H14-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H14→partner) and Y-score (partner→OR5H14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR2M5 →	+0.016	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TMEM95 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	NPY2R →	+0.003	+3.217	<.001	.006	3	1
LUNG_NSCLC_LUAD	TPD52L3 →	+0.395	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR2M5 by OR5H14 expression — SKIN

Explore this box plot interactively →