OR5H14

Across TCGA cell cohorts, OR5H14 mutation is significantly associated with the mutation status of many other genes, with 2,609 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5H14-associated genes across cancer lineages are NCAN, DEPDC5, and CD22. Each is linked with OR5H14 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR5H14-to-partner and partner-to-OR5H14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAN grouped by OR5H14-low versus OR5H14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H14→partner) and Y-score (partner→OR5H14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NCAN →	+2.263	+3.392	.001	.001	1	4
SKIN	DEPDC5 →	+4.094	+5.455	<.001	<.001	1	3
LARGE_INTESTINE	CD22 →	+3.584	+3.007	.008	.008	1	3
BLOOD_Leukemia	ZNF8 →	+4.309	+4.560	.007	.007	1	3
SKIN	RGPD3 →	+3.035	+3.321	.008	.008	1	3
BLOOD_Leukemia	CPAMD8 →	+2.572	+4.129	.009	.009	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,609 associations by consensus.

NCAN by OR5H14 expression — LARGE_INTESTINE

Explore this box plot interactively →