OR5H1

Across TCGA pan-cancer cohorts, OR5H1 Mutation is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated OR5H1 data layer compared with 6 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher OR5H1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR5H1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BRCA, PAAD, and UCEC are the cancer types where OR5H1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.805	0.963	<.001	26	view →
PAAD	OS	Median	All	0.131	0.613	.001	15	view →
UCEC	DFS	Median	All	1.000	0.830	.027	14	view →
OV	OS	Median	II,III,IV	0.511	0.844	<.001	12	view →
HNSC	OS	Median	IV	0.192	0.641	.011	12	view →
SKCM	DFS	Median	III,IV	0.058	0.648	.001	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR5H1–BRCA (OS)

Open the BRCA breakdown →