OR5G3

Across TCGA pan-cancer cohorts, OR5G3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR5G3’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR5G3 RNA is repressed in tumor relative to normal tissue. In most cancer types OR5G3 is over-expressed in tumor, although a few such as LUSC and LIHC show the opposite, repressed pattern.

LUSC, KICH, and LUAD are the cancer types where OR5G3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR5G3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	III,IV	−0.150	.023	2	view →
KICH	All	All	+0.041	.018	2	view →
LUAD	All	All	+0.151	.022	1	view →
LIHC	Male	All	−0.011	.044	1	view →
THCA	All	All	−0.010	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR5G3–LUSC

Open the LUSC breakdown →