OR5F1

Across TCGA patient cohorts, OR5F1 mutation is significantly associated with the RNA expression of many other genes, with 1,972 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5F1-associated genes across cancer lineages are KCNJ15, GBP4, and APOL3. Each is linked with OR5F1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5F1-to-partner and partner-to-OR5F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNJ15 grouped by OR5F1-low versus OR5F1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5F1→partner) and Y-score (partner→OR5F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	KCNJ15 →	-0.883	-1.925	<.001	.004	3	3
UCEC	GBP4 →	+0.767	+1.736	.002	.007	3	3
UCEC	APOL3 →	+0.819	+2.070	<.001	.001	3	3
SKCM	C12orf65 →	+0.373	+2.794	.002	<.001	3	3
COAD	RNU7-161P →	+0.273	+5.568	<.001	<.001	3	2
UCEC	SAP18 →	+0.290	+2.956	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,972 associations by consensus.

KCNJ15 by OR5F1 expression — LUSC

Explore this box plot interactively →