OR5F1

Across TCGA cell cohorts, OR5F1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR5F1-associated genes across cancer lineages are H2BC1, H2AC1, and IFNL2. Each is linked with OR5F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5F1-to-partner and partner-to-OR5F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H2BC1 grouped by OR5F1-low versus OR5F1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5F1→partner) and Y-score (partner→OR5F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	H2BC1 →	+0.325	+4.977	<.001	.002	3	1
SOFT_TISSUE	H2AC1 →	+0.145	+4.977	<.001	.002	3	1
SOFT_TISSUE	IFNL2 →	+0.069	+4.635	<.001	.003	3	1
LUNG_SCLC	TMIGD3 →	+0.512	+3.817	<.001	.004	3	1
LUNG_SCLC	CRYGC →	+0.032	+4.058	<.001	.007	3	1
LUNG_SCLC	TRIM60 →	+0.004	+4.058	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

H2BC1 by OR5F1 expression — SOFT_TISSUE

Explore this box plot interactively →