OR5E1P

Across TCGA pan-cancer cohorts, OR5E1P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of OR5E1P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR5E1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR5E1P is over-expressed in tumor, although a few such as KIRC and LUAD show the opposite, repressed pattern.

KIRC, LUAD, and BRCA are the cancer types where OR5E1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR5E1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.092	<.001	12	view →
LUAD	Female	II,III,IV	−0.346	<.001	6	view →
BRCA	All	III,IV	−0.314	<.001	6	view →
KICH	All	All	−0.065	.008	3	view →
THCA	All	All	+0.019	.001	3	view →
KIRP	Male	All	−0.085	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

OR5E1P–KIRC

Open the KIRC breakdown →