OR5D18

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5D18 mutation is significantly associated with the RNA expression of many other genes, with 2,359 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5D18-associated genes across cancer lineages are SKA1, FEN1, and RAD51. Each is linked with OR5D18 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR5D18-to-partner and partner-to-OR5D18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5D18→partner) and Y-score (partner→OR5D18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADSKA1 →+1.032+3.196<.001.00934
UCECFEN1 →+0.543+3.595.002.00134
UCECRAD51 →+0.721+2.332<.001<.00134
LUSCRAD54L →+0.522+3.816.003<.00134
UCECSNRPA1 →+0.346+2.831.002.00134
UCECCCDC163 →+0.506+2.534<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,359 associations by consensus.

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