Across TCGA patient cohorts, OR5B17 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR5B17-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, IRS1, and p21. Each is linked with OR5B17 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B17-to-partner and partner-to-OR5B17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B17→partner) and Y-score (partner→OR5B17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.550	+2.584	.031	.011	3	2
SKCM	IRS1 →	+0.158	+3.169	.025	.018	3	1
SKCM	p21 →	-0.743	-3.459	<.001	.005	3	1
SKCM	Akt_pS473 →	-0.593	-2.584	.018	.011	3	1
SKCM	Akt_pT308 →	-0.601	-3.446	.009	.005	3	1
SKCM	PDK1 →	-0.105	-2.533	.037	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

OR5B17 survival (RNA) · tumor vs normal (RNA) · all OR5B17 data types