OR5AU1

Across TCGA pan-cancer cohorts, OR5AU1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR5AU1 data layer compared with 9 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher OR5AU1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR5AU1 expression acts as an unfavorable survival marker.

BRCA, BLCA, and KICH are the cancer types where OR5AU1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.112	0.578	.007	24	view →
BLCA	OS	Median	III,IV	0.132	0.684	<.001	18	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
LIHC	OS	Median	All	0.015	0.784	<.001	12	view →
COAD	OS	Median	III,IV	0.239	0.791	.014	6	view →
HNSC	DFS	Median	All	0.132	0.625	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR5AU1–BRCA (OS)

Open the BRCA breakdown →