OR5AS1

Across TCGA patient cohorts, OR5AS1 mutation is significantly associated with the RNA expression of many other genes, with 2,948 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AS1-associated genes across cancer lineages are GUCA1B, EIF2B2, and ALDOAP2. Each is linked with OR5AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5AS1-to-partner and partner-to-OR5AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA1B grouped by OR5AS1-low versus OR5AS1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AS1→partner) and Y-score (partner→OR5AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GUCA1B →	+0.466	+1.854	.002	.005	3	3
UCEC	EIF2B2 →	+0.481	+2.949	<.001	<.001	3	3
SKCM	ALDOAP2 →	+0.185	+2.832	<.001	.002	3	3
SKCM	UBBP3 →	+0.270	+1.905	.001	.004	3	3
UCEC	ANXA2P2 →	+0.720	+2.137	.001	.001	3	3
UCEC	ZNHIT3 →	+0.370	+2.158	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,948 associations by consensus.

GUCA1B by OR5AS1 expression — SKCM

Explore this box plot interactively →