OR5AS1

Across TCGA cell cohorts, OR5AS1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR5AS1-associated genes across cancer lineages are FGF23, SPPL2C, and TARM1. Each is linked with OR5AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AS1-to-partner and partner-to-OR5AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGF23 grouped by OR5AS1-low versus OR5AS1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AS1→partner) and Y-score (partner→OR5AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	FGF23 →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	SPPL2C →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	TARM1 →	+0.026	+5.087	<.001	.004	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
SKIN	MS4A6E →	+0.040	+5.415	<.001	.004	3	1
SKIN	OR10H5 →	+0.012	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

FGF23 by OR5AS1 expression — URINARY_TRACT

Explore this box plot interactively →