OR5AR1

Across TCGA pan-cancer cohorts, OR5AR1 Mutation is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated OR5AR1 data layer compared with 6 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OR5AR1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR5AR1 expression acts as an unfavorable survival marker.

LUAD, LIHC, and SCLC are the cancer types where OR5AR1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.113	0.669	<.001	26	view →
LIHC	OS	Median	All	0.163	0.779	<.001	24	view →
SCLC	OS	Median	IV	0.137	0.548	.004	18	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
COAD	OS	Median	All	0.175	0.616	.005	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
GBM	OS	Median	All	0.121	0.415	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR5AR1–LUAD (OS)

Open the LUAD breakdown →