OR5AR1

Across TCGA patient cohorts, OR5AR1 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AR1-associated genes across cancer lineages are VEGFR2, Notch1, and p21. Each is linked with OR5AR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AR1-to-partner and partner-to-OR5AR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VEGFR2 grouped by OR5AR1-low versus OR5AR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AR1→partner) and Y-score (partner→OR5AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VEGFR2 →	+0.343	+2.013	.010	.018	3	2
UCEC	Notch1 →	+0.143	+3.183	.024	.009	3	1
UCEC	p21 →	+0.218	+2.700	.011	.006	3	1
UCEC	ATM →	-0.521	-2.000	.010	.032	3	1
UCEC	Caspase-8 →	-0.273	-2.700	.016	.006	2	1
UCEC	Annexin-1 →	+0.835	+2.000	<.001	.032	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

VEGFR2 by OR5AR1 expression — UCEC

Explore this box plot interactively →