OR5AR1

Across TCGA cell cohorts, OR5AR1 mutation is significantly associated with the RNA expression of many other genes, with 262 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5AR1-associated genes across cancer lineages are DEFB132, RAD51C, and MED31. Each is linked with OR5AR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AR1-to-partner and partner-to-OR5AR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB132 grouped by OR5AR1-low versus OR5AR1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AR1→partner) and Y-score (partner→OR5AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DEFB132 →	+0.012	+5.029	<.001	.006	3	2
LARGE_INTESTINE	RAD51C →	+1.024	+3.299	<.001	.004	3	1
LARGE_INTESTINE	MED31 →	+0.881	+3.212	<.001	.006	3	1
LARGE_INTESTINE	NDUFC1 →	+0.726	+3.212	.001	.006	3	1
LARGE_INTESTINE	APBA3 →	+0.636	+3.212	.001	.006	3	1
LARGE_INTESTINE	COMMD2 →	+0.530	+3.212	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 262 associations by consensus.

DEFB132 by OR5AR1 expression — LUNG_SCLC

Explore this box plot interactively →