OR5AP2

Across TCGA pan-cancer cohorts, OR5AP2 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR5AP2 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher OR5AP2 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated OR5AP2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LGG, and BLCA are the cancer types where OR5AP2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.621	.012	28	view →
LGG	OS	Median	All	0.194	0.830	<.001	6	view →
BLCA	DFS	Median	All	0.174	0.625	.023	6	view →
LUAD	DFS	Median	IV	0.342	0.893	<.001	6	view →
LIHC	DFS	Median	All	0.044	0.553	<.001	6	view →
COAD	DFS	Median	All	0.521	0.785	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR5AP2–UCEC (DFS)

Open the UCEC breakdown →