Across TCGA pan-cancer cohorts, OR5AO1P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR5AO1P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR5AO1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR5AO1P is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
LUSC and KIRC are the cancer types where OR5AO1P tumor–normal differential expression is most reproducible.