OR5AN1

Across TCGA patient cohorts, OR5AN1 mutation is significantly associated with the RNA expression of many other genes, with 519 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AN1-associated genes across cancer lineages are BRK1, RNA5SP410, and RNU6-1028P. Each is linked with OR5AN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AN1-to-partner and partner-to-OR5AN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BRK1 grouped by OR5AN1-low versus OR5AN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AN1→partner) and Y-score (partner→OR5AN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BRK1 →	+0.410	+3.711	.008	<.001	3	2
LUAD	RNA5SP410 →	+0.250	+5.327	<.001	.002	3	2
LUAD	RNU6-1028P →	+0.334	+5.000	<.001	.003	3	2
UCEC	CCDC15 →	+0.492	+2.617	.002	.006	3	2
UCEC	RRM1 →	+0.837	+3.330	.003	.005	3	2
UCEC	LSM3 →	+0.650	+3.212	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 519 associations by consensus.

BRK1 by OR5AN1 expression — UCEC

Explore this box plot interactively →