OR5AN1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5AN1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AN1-associated genes across cancer lineages are GMP, Eosinophils, and Endothelial cells. Each is linked with OR5AN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5AN1-to-partner and partner-to-OR5AN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by OR5AN1-low versus OR5AN1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AN1→partner) and Y-score (partner→OR5AN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCGMP →+0.039+3.264.030.04633
LUSCEosinophils →+0.030+3.173.039.04931
UCECEndothelial cells →-0.040-2.978.025.03631
UCEClymphatic Endothelial cells →-0.025-2.531.025.01231
UCECpDC →+0.061+3.202.007.00931
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GMP by OR5AN1 expression — LUSC

Box plot of GMP in OR5AN1-low vs OR5AN1-high samples in LUSC.

Explore this box plot interactively →

Exploration