OR5AN1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR5AN1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5AN1-associated genes across cancer lineages are SPINK9, TMEM244, and OR4D10. Each is linked with OR5AN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AN1-to-partner and partner-to-OR5AN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPINK9 grouped by OR5AN1-low versus OR5AN1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AN1→partner) and Y-score (partner→OR5AN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINSPINK9 →+0.065+5.415<.001.00431
LARGE_INTESTINETMEM244 →+0.691+5.415<.001.00431
LARGE_INTESTINEOR4D10 →+0.006+4.977<.001.00731
BLOOD_LymphomaC11orf97 →+2.125+5.209<.001.00531
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SPINK9 by OR5AN1 expression — SKIN

Box plot of SPINK9 in OR5AN1-low vs OR5AN1-high samples in SKIN.

Explore this box plot interactively →

Exploration