OR5AK2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5AK2 mutation is significantly associated with the RNA expression of many other genes, with 2,537 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AK2-associated genes across cancer lineages are TUBGCP5, RNU4-26P, and MYO19. Each is linked with OR5AK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AK2-to-partner and partner-to-OR5AK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBGCP5 grouped by OR5AK2-low versus OR5AK2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AK2→partner) and Y-score (partner→OR5AK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTUBGCP5 →+0.409+2.447.005.00132
HNSCRNU4-26P →+0.268+7.954<.001.00832
UCECMYO19 →+0.465+2.931.004<.00132
UCECIMMP1L →+0.477+2.425<.001.00232
UCECMTA2 →+0.505+3.627<.001.00132
UCECCPSF7 →+0.406+3.491.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,537 associations by consensus.

TUBGCP5 by OR5AK2 expression — UCEC

Box plot of TUBGCP5 in OR5AK2-low vs OR5AK2-high samples in UCEC.

Explore this box plot interactively →

Exploration