OR5A1

Across TCGA patient cohorts, OR5A1 mutation is significantly associated with the RNA expression of many other genes, with 618 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OR5A1-associated genes across cancer lineages are RN7SKP295, MIR3684, and NUTF2. Each is linked with OR5A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5A1-to-partner and partner-to-OR5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP295 grouped by OR5A1-low versus OR5A1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5A1→partner) and Y-score (partner→OR5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP295 →	+0.235	+4.314	<.001	.009	3	3
BLCA	MIR3684 →	+0.497	+3.840	<.001	.006	3	3
LUAD	NUTF2 →	+0.353	+2.596	.006	.006	3	3
GBM	RARRES2P6 →	+0.574	+5.149	<.001	.007	3	2
UCEC	SDK2 →	-1.027	-3.700	.004	.001	3	2
UCEC	CENATAC →	+0.433	+3.345	.009	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 618 associations by consensus.

RN7SKP295 by OR5A1 expression — BLCA

Explore this box plot interactively →