OR5A1

Across TCGA patient cohorts, OR5A1 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR5A1-associated genes across cancer lineages are eEF2, JNK_pT183_Y185, and RBM15. Each is linked with OR5A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5A1-to-partner and partner-to-OR5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by OR5A1-low versus OR5A1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5A1→partner) and Y-score (partner→OR5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	eEF2 →	+0.266	+3.009	.004	.019	3	1
LUSC	JNK_pT183_Y185 →	-0.122	-2.990	.043	.036	3	1
LUSC	RBM15 →	+0.390	+3.009	.035	.019	2	2
LUSC	VHL →	+1.009	+3.009	.023	.019	3	1
LUSC	beta-Catenin →	+0.673	+3.013	.011	.018	3	1
SKCM	DJ-1 →	+0.179	+3.000	.047	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

eEF2 by OR5A1 expression — LUSC

Explore this box plot interactively →