OR5A1

Across TCGA cell cohorts, OR5A1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5A1-associated genes across cancer lineages are SLN, TRHR, and CFHR2. Each is linked with OR5A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5A1-to-partner and partner-to-OR5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLN grouped by OR5A1-low versus OR5A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5A1→partner) and Y-score (partner→OR5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLN →	+0.143	+3.334	.004	.008	3	1
LARGE_INTESTINE	TRHR →	+0.049	+2.906	<.001	.008	3	1
LARGE_INTESTINE	CFHR2 →	+0.032	+3.700	<.001	.009	3	1
LUNG_SCLC	OR1L6 →	+0.038	+5.029	<.001	.006	3	1
LUNG_SCLC	GDF2 →	+0.023	+5.643	<.001	.002	3	1
SKIN	C5orf52 →	+0.046	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

SLN by OR5A1 expression — LARGE_INTESTINE

Explore this box plot interactively →